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PPI Prediction Challenge Key

Binder 1: GSVKVKFIFSGEEKEVDTSKIHAVFRNGKYVTFFYDDNGKHGFGSVLEKDAPKELLDMLARAEREKKL

Target: KRASG12D

MTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKCVIM

 

Binder 2:

GSVKVKFSHAGEEKEVDTSKIRIVCRAGKLVYFLYDDNGKRGCGLVYEKDAPKELLDMLARAEREKKL

Target: DltD (strep)

MDYYKVKDNSIRYSTSYEKYKSRDILTSNITPNTLVLMGSSELVATINEDYHPNKIFNYNDFNIMQIGTSYSQNIIQATTLGSIEGSMTKRKVAIVESVQWFEKDGTHQDAFLNKASQEHIFHMLDNGKISKETKEKLINRIIEITKGNKQQNDIYKKYKSYFIDGKGTIVDKKLLEFENAMYSFKLKQTFYQKHAKSDYPSLGDKTPDYDWQKMTNQFVEEVKQKTDNNDYAVDNNYYNTYLKDRYASLKDSNKDLSYLESPEYSDMELFLTVAKELGIEVEVIIFPVNGKWNDYTGVSREMREKTYKKIEDVAKSHGATVLNYGNREYDDYFLFDVMHVGVKGWMEVEKELYKFANQAN

 

Binder 3:

GSVKVKFVVRGEEKEVDTSKIRSVWRGGKWVDFSYDDNGKQGYGYVLEKDAPKELLDMLARAEREKKL

Target: (SasA) nonbinder

 

Binder 4:

VDNKFNKEGDTAVLEIGHLPNLNLHQQYAFLHSLYNDPSQSANLLAEAKKLNDAQAPK

Target: GABARAP

MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL

 

Binder 5:

VDNKFNKELFYAFHQIYALPNLNAAQVRAFVGSLDDDPSQSANLLAEAKKLNDAQAPK

Target: MBP

MKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK

 

Binder 6

VDNKFNKEPRAARLEITVLPNLNREQGGAFIVSLWDDPSQSANLLAEAKKLNDAQAPK

Target: (PD-L1) nonbinder

 

Binder 7:

VDNKFSKEVFTAFDQIGGLPNLNLCQKDAFICSLVDDPSQSANLLAEAKKLNDAQAPK

Target: Myc DBD

MNVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQL

 

Binder 8:

VDNKFSKEVGAADGEIVGLPNLNGSQKIAFLRSLVNDPSQSANLLAEAKKLNDAQAPK

Target: mCherry

MVSKGEEDNMAIIKEFMRFKVHMEGSVNGHEFEIEGEGEGRPYEGTQTAKLKVTKGGPLPFAWDILSPQFMYGSKAYVKHPADIPDYLKLSFPEGFKWERVMNFEDGGVVTVTQDSSLQDGEFIYKVKLRGTNFPSDGPVMQKKTMGWEASSERMYPEDGALKGEIKQRLKLKDGGHYDAEVKTTYKAKKPVQLPGAYNVNIKLDITSHNEDYTIVEQYERAEGRHSTGGMDELYK

 

Binder 9:

VDNKFSKEWIDAFVEINFLPNLNRNQRCAFVNSLLNDPSQSANLLAEAKKLNDAQAPK

Target: KIX

MGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRL

 

Binder 10:

VDNKFSKEWSDAVYEIGRLPNLNGYQGGAFINSLVNDPSQSANLLAEAKKLNDAQAPK

Target: Mdm2

MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDS

 

Binder 11:

VDNKFTKEVDDASFEILYLPNLNDFQENAFLVSLSDDPSQSANLLAEAKKLNDAQAPK

Target: LC3B

MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFGMKLSV

 

Binder 12:

VDNKFTKEVDSAVFEIHILPNLNDYQRVAFIFSLFDDPSQSANLLAEAKKLNDAQAPK

Target: IFNG

MQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQ

 

Binder 13:

VDNKFYKEVDAAASEICSLPNLNRNQRSAFICSLYNDPSQSANLLAEAKKLNDAQAPK

Target HIF-1a:

MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDAGDLDIEDDMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDL

 

Binder 14:

VKVKFFDAGEEKEVDTSKIFPVPRYGKYVIFYYDDNGKVGRGSVNEKDAPKELLDMLARAEREKKL

Target: 14-3-3

MDKNELVQKAKQAEQAEDYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSEWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN


Binder 15:

VKVKFRRPGEEKEVDTSKIGYVHRVGKFVAFFYDDNGKIGSGTVSEKDAPKELLDMLARAEREKKL

Target: Calpro het 12

MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTPGGSGGSGGSGGSMLTELEKALNSIIDVYHKYSLIKGNFHAVYRDDLKKLLETECPQYIRKKGADVWFKELDINTDGAVNFQEFLILVIKMGVAAHKKSHEESHKE

 

Binder 16:

VKVKFSSAGEEKEVDTSKIFVVRRLGKYVGFTYDDNGKAGLGLVCEKDAPKELLDMLARAEREKKL

Target Max:

MDKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQGEHP

 

Binder 17:

VKVKFSYAGEEKEVDTSKIYHVSRLGKDVIFCYDDNGKVGSGAVFEKDAPKELLDMLARAEREKKL

 

Target RAF:

MSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFL


Binder 18:

VKVKFTDCGEEKEVDTSKITYVIRFGKFVDFDYDDNGKIGSGAVREKDAPKELLDMLARAEREKKL

Target: DltD (ef)

MDISNPETIRRASSSMSVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGTQSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKKVTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEVFSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIRAHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQEMLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEENHITASKYHLDDAFFSKSWQHQIPDKLQLK

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