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Congrats to Michael for his paper in Chemical Science on a new method to probe cys PTM erasers!

  • Writer: bryandickinson
    bryandickinson
  • Sep 10, 2017
  • 1 min read

Michael's work lays the foundation for a new approach to measure the activities of cysteine PTM eraser proteins in live cells. The method uses a "ratiometric" probe, which correlate target activity to a change in emission of two wavelengths of a probe. In this way, target activities can be better quantified in live cells, especially in heterogenous samples such as primary tissues. Michael applied his approach to study lipid regulatory proteins. Way to go!


 
 
 

5 Comments


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Ellen Litwack
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Sep 23, 2025

Congratulations to Michael and the team for making strides in chemical science research! The development of a ratiometric probe for measuring cysteine PTM erasers' activity in live cells is a fantastic achievement and truly highlights the importance of innovative approaches in scientific study.


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